Mar 24, 2020
Study Shows CRISPR Effectiveness Against Colitis Pathogen
Research at NC State demonstrates that the CRISPR-Cas system can be used to effectively target and eliminate specific gut bacteria, in this case Clostridioides difficile, the pathogen that causes colitis – a chronic, degenerative disease of the colon. In a proof-of-concept study published in the journal mBio, researchers including Rodolphe Barrangou, Todd R. Klaenhammer Distinguished Professor of Food, Bioprocessing and Nutrition Sciences, were able to show pathogen reductions in experiments conducted both on the lab bench and in mice.